Building a better reference genome

GRAF at a glance

Canonical Linear Reference genomes are now 20+ years old and do not account for all genomic variation. Read mapping against linear references leads to reference bias. This systemic blindness is a profound barrier to accurate genomic data analysis, especially in non-European populations.

GRAF for discovery

Run fast and accurate genomic analyses using genome graphs. GRAF represents genetic variation in a population by enhancing the standard reference. The canonical linear reference serves as the backbone while edges represent alternate sequences.

GRAF for pan genome-aware secondary NGS analysis

Velsera has pioneered graph reference-based secondary analysis technology since 2014. The technology and patent portfolio are now available as robust, stable, scalable, and deeply validated pipelines ready for deployment in pharma discovery environments. The draft human pan-genome reference presented by the HPRC1 has generated broad awareness of how to solve the reference bias problem. State-of-the-art graph and pan-genome-based sequence analysis is now becoming the standard.

Clinical Diagnostic Laboratories

DEVELOP NEW REVENUE STREAMS BY COMMERCIALIZING YOUR TESTS

Have you got a promising diagnostic test in development? Velsera can partner with you to bring new, promising tests to market by creating, integrating, hosting and/or deploying custom-developed NGS analysis pipelines on Seven Bridges. Additionally, we can help your future laboratory customers with validation and regulatory support to ensure compliance, as well as Revenue Cycle Management support to enable reimbursement – increasing the uptake from customers. Optionally, tertiary CGW reporting is available to create a fully integrated secondary & tertiary analysis package for your test.

NGS Assay & Equipment Manufacturers

BRING NEW TESTS AND EQUIPMENT TO MARKET

Have you got a promising diagnostic test in development? Or do you have novel equipment that you want to drive uptake of in the clinical setting? Velsera can partner with you to bring new, promising tests to market by creating, integrating, hosting and/or deploying custom-developed NGS analysis pipelines. Additionally, we can help your future laboratory customers with validation and regulatory support to ensure compliance, as well as Revenue Cycle Management support to enable reimbursement – increasing the uptake from customers. Optionally, tertiary CGW reporting is available to create a fully integrated secondary & tertiary analysis package for your test.

Biotech & Pharma

FOCUS ON INSIGHTS, NOT INFRASTRUCTURE

The volume of clinical-genomic data available to researchers is exploding. But without the right tools and advice it can be hard to cut through the noise and find the insights you need. Our best-in-class tools supported by our in-house Bioinformatics and Science teams can help you to do just this and accelerate your time to finding that next big breakthrough.

Non-profits & Government Agencies

BUILD ON THE BEST – OUR TECHNOLOGY IS WIDELY ADOPTED ALREADY

Velsera’s tools are already widely in use across government, academic and commercial research. Our teams of in-house Scientists can help engage this community to make better use of your assets – either to further your research interests, drive new revenue streams, or both!